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REXULTI (Brexpiprazole) - Canada Product Information
Rexulti is a medication used to treat certain mental health conditions. It is available in tablet form and comes in different strengths: 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, and 4 mg.
WHAT IS REXULTI USED FOR?
For Adults Diagnosed with:
Schizophrenia: Rexulti helps manage symptoms of schizophrenia, such as hallucinations, delusions, and disorganized thinking.
Major Depressive Disorder (MDD): Rexulti is used alongside antidepressants to treat depression in adults who have not responded well to previous antidepressant treatments.
IMPORTANT INFORMATION BEFORE TAKING REXULTI
Do Not Take Rexulti if You:
Are allergic to brexpiprazole or any of the ingredients in Rexulti.
Tell Your Doctor if You:
Have any medical conditions, including heart problems, diabetes, or a history of seizures.
Are pregnant, planning to become pregnant, or breastfeeding.
Are taking any other medications, including prescription, over-the-counter, vitamins, and herbal supplements.
HOW TO TAKE REXULTI
Follow your doctor's instructions on how to take Rexulti.
It is usually taken once daily, with or without food.
Do not change your dose or stop taking Rexulti without consulting your doctor.
POSSIBLE SIDE EFFECTS
Common Side Effects:
- Weight gain
- Headache
- Restlessness or difficulty staying still (akathisia)
- Dizziness
- Fatigue
- Increased appetite
Serious Side Effects:
- Increased risk of death in elderly people with dementia-related psychosis
- Neuroleptic Malignant Syndrome (NMS): Symptoms include high fever, stiff muscles, confusion, sweating, and changes in pulse or blood pressure. Seek immediate medical attention if you experience these symptoms.
- Tardive Dyskinesia: Involuntary movements of the face and body that may not go away even after stopping the medication.
- High blood sugar (hyperglycemia): Symptoms include feeling very thirsty, needing to urinate more than usual, feeling very hungry, feeling weak or tired, and feeling sick to your stomach.
- Low white blood cell count: Can increase the risk of infections.
- Falls: Rexulti may cause drowsiness or dizziness, which can increase the risk of falling.
STORAGE
Store at room temperature, away from moisture and heat. Keep out of reach of children.
SUPPLIED
Rexulti from Canada is dispensed in bottles of 30 tablets.
GENERAL ADVICE
Rexulti may affect your ability to drive or operate machinery. Do not engage in these activities until you know how Rexulti affects you.
Avoid drinking alcohol while taking Rexulti.
If you have any questions or concerns about taking Rexulti, talk to your doctor or pharmacist. Your health and well-being are important, and they can provide more detailed information tailored to your specific needs.
Reference: Rexulti Canada product monograph
Take Rexulti exactly as prescribed by your doctor, usually once daily with or without food. Do not change your dose or stop taking it without consulting your doctor. Swallow the tablet whole, and take it at the same time each day for the best effect.