Ozempic (Semaglutide)
Ozempic (Semaglutide)
Semaglutide
Product information
Ozempic for diabetes and weight loss - available online from Canada! Ozempic (semaglutide) is an injectable medication used to improve blood sugar control in adults with type 2 diabetes and to reduce the risk of major cardiovascular events. Off-label, it is commonly used for weight loss due to its appetite-suppressing effects. It works by mimicking the GLP-1 hormone, enhancing insulin secretion and reducing hunger. Ozempic is not recommended for type 1 diabetes or diabetic ketoacidosis.
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Ozempic (Semaglutide) - Canada Product Information
If you are looking for an even more cost effective supply of Ozempic 4 mg, it can be sourced from Singapore, please click here to learn more.
A video recording of the medication may be seen here
Ozempic works by helping your body to control blood sugar levels. It increases the amount of insulin your body releases when your blood sugar is high and reduces the amount of sugar your liver makes. It also slows down how quickly food leaves your stomach, which helps control blood sugar levels after eating.
WHO SHOULD USE OZEMPIC?
Ozempic is for adults with type 2 diabetes. It is used when diet and exercise alone are not enough to control your blood sugar levels. Your doctor might prescribe Ozempic if you cannot take metformin or if you are already taking other diabetes medications but still need help managing your blood sugar.
WHO SHOULD NOT USE OZEMPIC?
Do not use Ozempic if you have:
- A personal or family history of a type of thyroid cancer called medullary thyroid carcinoma.
- Multiple endocrine neoplasia syndrome type 2 (MEN 2).
- An allergy to semaglutide or any of the ingredients in Ozempic.
- You are pregnant or planning to become pregnant. Stop Ozempic at least 2 months before a planned pregnancy.
- You are breastfeeding.
DOSAGE AND ADMINISTRATION
Ozempic Dosing Chart
Week | Dose | Instructions |
---|---|---|
1-4 | 0.25 mg weekly | Start with 0.25 mg once a week. This is a starting dose to help your body adjust to the medication. |
5-8 | 0.5 mg weekly | Increase to 0.5 mg once a week. This is the usual maintenance dose. |
9+ | 1 mg weekly (if needed) | If additional blood sugar control is needed, your doctor may increase the dose to 1 mg once a week. |
Important Notes
- Injection Day: Choose a specific day of the week for your injection. You can change the day as long as there are at least 2 days (48 hours) between doses.
- Missed Dose: If you miss a dose and it's within 5 days of your scheduled day, take it as soon as possible. If more than 5 days have passed, skip the missed dose and take the next dose on your regular scheduled day.
- Injection Sites: Inject under the skin in your abdomen, thigh, or upper arm. Rotate injection sites with each dose to avoid skin problems.
Example Dosing Schedule
Month 1 (Weeks 1-4)
Week | Day | Dose |
---|---|---|
1 | Monday | 0.25 mg |
2 | Monday | 0.25 mg |
3 | Monday | 0.25 mg |
4 | Monday | 0.25 mg |
Month 2 (Weeks 5-8)
Week | Day | Dose |
---|---|---|
5 | Monday | 0.5 mg |
6 | Monday | 0.5 mg |
7 | Monday | 0.5 mg |
8 | Monday | 0.5 mg |
Month 3 and Beyond (Week 9+)
Week | Day | Dose |
---|---|---|
9 | Monday | 0.5 mg or 1 mg |
10 | Monday | 0.5 mg or 1 mg |
11 | Monday | 0.5 mg or 1 mg |
12 | Monday | 0.5 mg or 1 mg |
Make sure to follow your doctor's instructions regarding your dose and schedule. Use this chart to help keep track of your doses and ensure you are taking Ozempic correctly. If you have any questions or concerns, please consult your healthcare provider.
Using the 4 mg Pen for Lower Doses of 0.25 mg and 0.5 mg
To help reduce costs, some healthcare providers may recommend using the Ozempic 4 mg pen for patients prescribed lower doses like 0.25 mg or 0.5 mg. With this approach, patients can follow a “click counting” method to measure approximate doses:
- 0.25 mg: 18 clicks
- 0.5 mg: 37 clicks
- 0.75 mg: 55 clicks
- 1 mg: 74 clicks
- 1.25 mg: 92 clicks
- 1.5 mg: 111 clicks
The DrugsByCanada.com click pen guide can be found here
A video showcasing how to use the click system may be seen here
POSSIBLE SIDE EFFECTS
Common side effects include:
- Nausea
- Diarrhea
- Vomiting
- Stomach pain
- Constipation
Some serious side effects include:
- Thyroid tumors: Contact your doctor if you notice a lump in your neck, hoarseness, trouble swallowing, or shortness of breath.
- Pancreatitis: Severe stomach pain that may spread to your back, nausea, and vomiting.
- Low blood sugar (hypoglycemia): Especially if you use Ozempic with other diabetes medications like insulin.
- Kidney problems: Report any symptoms of dehydration such as vomiting or diarrhea to your doctor.
PRECAUTIONS
- Regular Monitoring: Check your blood sugar levels regularly to ensure Ozempic is working effectively.
- Pregnancy: Avoid using Ozempic if you are pregnant or breastfeeding. Inform your doctor immediately if you become pregnant while taking Ozempic.
- Other Medications: Inform your doctor about all other medications you are taking as Ozempic can interact with some of them.
STORAGE
- Store unused Ozempic pens in the refrigerator.
- After first use, you can store your Ozempic pen at room temperature for up to 56 days.
- Do not freeze Ozempic pens.
SUPPLIED
Ozempic from Canada is available in pre-filled multi-dose pens. There are two formats:
- Ozempic 0.68mg/mL: Red labelled 3 mL pen, contains 6 pen needle tips
- Ozempic 1.34mg/mL: Turquoise labelled 3 mL pen, contains 4 pen needle tips
Note: you may need to purchase additional pen needle tips if you are using the “click” method with the 1mg/dose (1.34 mg/mL) pen.
Call your doctor if you experience any severe side effects or if you have concerns about how Ozempic is affecting your health. Regular check-ups will help manage your diabetes effectively while using Ozempic.
Reference: Ozempic Canada product monograph
Product Video: Ozempic 4 mg Pen - Buying from Canada
Off-Label Uses of Ozempic and Respective Doses
1. Weight Loss
Ozempic (semaglutide) is often used off-label for weight loss. While it is primarily approved for managing type 2 diabetes, its ability to promote weight loss has led to its off-label use for this purpose.
- Dosage for Weight Loss: Studies have used doses of 0.5 mg and 1 mg weekly, with some studies exploring higher doses up to 2.4 mg weekly to maximize weight loss effects. However, a common off-label approach is to start with the same initial dose as for diabetes management, i.e., 0.25 mg weekly for the first 4 weeks, then increase to 0.5 mg weekly, and potentially up to 1 mg or more based on the patient's response and tolerance.
2. Cardiovascular Risk Reduction
Although not officially labeled for this use, Ozempic has shown benefits in reducing cardiovascular risk factors in patients with type 2 diabetes, such as improving cholesterol levels and reducing blood pressure.
- Dosage: The doses used for cardiovascular benefits typically align with those used for diabetes management, starting at 0.25 mg weekly and increasing to 0.5 mg or 1 mg weekly.
Note on Safety and Monitoring
When using Ozempic off-label, it is crucial to do so under the supervision of a healthcare provider. They will monitor for any potential side effects, such as gastrointestinal issues, and adjust the dosage accordingly to ensure safety and effectiveness.
Conclusion
Ozempic is commonly used off-label for weight loss, with doses ranging from 0.25 mg to 2.4 mg weekly, depending on individual response and medical supervision. It also offers cardiovascular benefits at similar dosages. Always consult with a healthcare provider before starting any off-label use of medication.