Pristiq Tablets (Desvenlafaxine Extended Release)

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Pristiq Tablets (Desvenlafaxine Extended Release)

Desvenlafaxine Succinate


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Pristiq - available online from Canada! Pristiq (desvenlafaxine) is an antidepressant used to treat major depressive disorder in adults. It works by balancing serotonin and norepinephrine in the brain. Common side effects include nausea, dry mouth, dizziness, and insomnia. Do not stop taking it suddenly. Inform your doctor of any other medications you're taking and any health conditions. Regular monitoring by your doctor is essential for safe and effective use.

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PRISTIQ - Canada Product Information



Pristiq is a medication used to treat major depressive disorder (MDD) in adults. It helps improve mood, feelings of well-being, and energy levels by affecting the balance of certain natural substances (serotonin and norepinephrine) in the brain.


How to Take Pristiq:

  • Take Pristiq exactly as prescribed by your doctor.
  • The usual starting dose is 50 mg once daily, with or without food.
  • Swallow the tablet whole; do not crush, chew, or dissolve it.
  • Try to take it at the same time every day.
  • If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not take two doses at once.

  • Important Warnings:

    Do not stop taking Pristiq suddenly. This can cause withdrawal symptoms like dizziness, headache, irritability, and insomnia. Your doctor will guide you on how to taper off the medication safely.

    Suicidal Thoughts: Especially in young adults under 24, there may be an increased risk of suicidal thoughts when starting Pristiq. Monitor for any sudden changes in mood, behavior, or thoughts, and contact your doctor immediately if you have concerns.


    Before Taking Pristiq:

  • Inform your doctor if you have any allergies, especially to desvenlafaxine or venlafaxine.
  • Discuss your medical history, particularly if you have high blood pressure, heart problems, liver or kidney disease, seizures, or a history of bipolar disorder.
  • Tell your doctor about all the medications you are taking, including prescription, over-the-counter drugs, and herbal supplements, as Pristiq can interact with certain medications.

  • Possible Side Effects:


    Common side effects include:

    • Nausea
    • Dry mouth
    • Dizziness
    • Insomnia (trouble sleeping)
    • Sweating
    • Constipation
    • Loss of appetite

    Contact your doctor if you experience severe side effects such as:

    • Severe headache
    • Unusual mood changes
    • Eye pain or vision changes
    • Seizures

    Serotonin Syndrome:

    Pristiq can increase serotonin levels, leading to a rare but serious condition called serotonin syndrome. Symptoms include hallucinations, agitation, rapid heartbeat, dizziness, flushing, muscle tremors, or stiffness. Seek immediate medical attention if you experience these symptoms.


    Use During Pregnancy and Breastfeeding:

  • If you are pregnant or planning to become pregnant, discuss the potential risks and benefits with your doctor.
  • Pristiq can pass into breast milk. If you are breastfeeding, consult your doctor to weigh the potential risks and benefits.

  • Storage:

  • Store Pristiq at room temperature, away from light and moisture.
  • Keep out of reach of children and pets.

  • Supplied:

    Pristiq from Canada is packaged in a carton with foil blisters containing 30 tablets.


    When to Seek Help:

  • If you have thoughts of harming yourself or others, seek immediate medical help.
  • Contact your doctor if your depression worsens or if you experience any new or unusual symptoms.

  • Pristiq can be an effective treatment for depression, but it’s essential to take it as prescribed and keep in touch with your healthcare provider. Regular follow-ups will help ensure the medication is working effectively and safely for you.



    Reference: Pristiq Canada product monograph