Silenor (Doxepin)

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Silenor® (Doxepin) – Canada Product Information

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What is Silenor?

Silenor is a prescription medication designed to help adults stay asleep throughout the night. If you often wake up in the middle of the night or too early in the morning, Silenor can help you achieve a restful and uninterrupted sleep.

Silenor is available in 3 mg and 6 mg tablets. It’s suitable for adults and older adults (65+ years) but is not intended for children under 18 years of age.

Why Choose Silenor?

Silenor is backed by clinical trials and helps you stay asleep longer. Unlike some sleep aids, Silenor has no potential for abuse or physical dependence.

Who Should Not Take Silenor?

You should not take Silenor if you have untreated narrow-angle glaucoma, trouble urinating, or are taking a monoamine oxidase inhibitor (MAOI) or have taken one in the past 14 days. Do not take Silenor if you are allergic to doxepin or any of the tablet’s ingredients.

What to Tell Your Doctor Before Taking Silenor

Before starting Silenor, inform your healthcare provider if you have a history of depression, suicidal thoughts, or other psychiatric conditions. Let your doctor know if you suffer from sleep apnea, liver disease, or if you are pregnant, planning to become pregnant, or breastfeeding. Regular alcohol consumption or taking other medications, including over-the-counter drugs or herbal supplements, should also be discussed with your healthcare provider.

How to Take Silenor

Take Silenor within 30 minutes of bedtime. Avoid taking Silenor within 3 hours of a meal, as food can delay its effects. Ensure you can dedicate 7 to 8 hours to sleep before engaging in daily activities. Once you’ve taken Silenor, limit your activities to preparing for bed.

Common Side Effects of Silenor

While Silenor is generally well-tolerated, some patients may experience tiredness or feeling "drugged," dizziness, dry mouth, nausea, or headache.

Serious Side Effects to Watch For

Sleepwalking or “sleep-driving” may occur in rare cases, where people engage in activities like driving, eating, or making phone calls while not fully awake. These activities are often not remembered the next day. Contact your doctor immediately if this occurs. Worsening depression or suicidal thoughts should also be reported to your healthcare provider right away.

Drug Interactions

Inform your doctor of all medications you’re taking, as Silenor may interact with alcohol, sedatives or sleep aids, certain allergy medications (antihistamines), medications for depression, anxiety, or seizures, and monoamine oxidase inhibitors (MAOIs).

Missed a Dose?

If you forget to take Silenor, wait until your next scheduled bedtime to take it. Never take two doses at once.

Storage Instructions

Store Silenor at room temperature, between 59°F and 86°F. Protect the tablets from light and keep Silenor in a safe place, out of reach of children.

When to Contact Your Doctor

Contact your doctor if your sleep problems persist after 7–10 days or if you experience side effects like sleepwalking, suicidal thoughts, or other concerning symptoms.

Why Silenor is Effective

Silenor contains doxepin hydrochloride, which works by blocking certain receptors in the brain that can interrupt sleep. Its unique mechanism of action helps maintain sleep without the risks of dependence or abuse.

Ready for Restful Nights?

Talk to your doctor today to see if Silenor is right for you. With Silenor, you can regain control of your sleep and wake up feeling refreshed.

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Reference: Silenor Canada product monograph

Product Video: Canadian Silenor

Take Silenor within 30 minutes of bedtime, ensuring you can sleep for 7–8 hours. Avoid taking it within 3 hours of a meal to prevent delayed effects. After taking Silenor, limit activities to preparing for sleep. Do not take Silenor with alcohol or other sedatives. If you miss a dose, take it at your next scheduled bedtime. Always follow your doctor’s instructions for dosage and use.