Taltz Autoinjector

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Taltz (Ixekizumab) - Canada Product Information

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What is TALTZ and How Can It Help You?

TALTZ is a medication prescribed by your doctor to help treat the following conditions:

• Plaque Psoriasis: A skin condition that causes red, scaly, and sometimes itchy patches.
• Psoriatic Arthritis: A condition where joints become swollen and painful, often linked with psoriasis.
• Ankylosing Spondylitis: A condition causing inflammation in the spine, leading to back pain and stiffness.
• Non-radiographic Axial Spondyloarthritis: A type of spine inflammation that doesn't show up on X-rays but still causes discomfort.

TALTZ works by targeting a specific protein in your immune system, interleukin-17A, which causes inflammation. By blocking this protein, TALTZ helps reduce redness, swelling, and pain.

How to Take TALTZ

TALTZ is an injection given under your skin (subcutaneous injection). You may receive it in a healthcare setting, or after proper training, you can inject it yourself.

Steps for Self-Injection

1. Preparation: Take the TALTZ prefilled syringe or autoinjector out of the refrigerator 30 minutes before use to let it reach room temperature. Do not shake the syringe or autoinjector.
2. Inspect the Medicine: The liquid should be clear to slightly yellow. Do not use it if the liquid is cloudy, discolored, or has particles.
3. Choose the Injection Site: Common areas include the front of the thighs, abdomen (except near your belly button), or the outer upper arm. Avoid injecting into areas with cuts, bruises, or patches of psoriasis.
4. Inject: Follow the instructions provided during your training or in the leaflet included with the medicine.
5. Dispose Safely: Use a puncture-resistant container to dispose of the used syringe or autoinjector.

Missed a Dose?

If you forget to take your dose, inject it as soon as you remember. Then, continue with your regular schedule.

What to Expect

Benefits of TALTZ may include clearer skin, relief from itching and scaling, reduced joint pain and stiffness, better mobility, and improved flexibility and reduced pain in the back and joints.

Possible Side Effects

Common side effects include redness, swelling, or pain at the injection site, and colds or upper respiratory infections (e.g., runny nose or sore throat).
Less common but serious side effects include allergic reactions (e.g., swelling of the face, lips, or tongue; difficulty breathing), infections (e.g., fever, chills, or feeling unusually tired), or digestive issues like new or worsening diarrhea or abdominal pain.

What to Do

Call your doctor immediately if you notice any serious side effects. Always tell your doctor about your medical history, especially if you have a history of tuberculosis (TB), Crohn’s disease, ulcerative colitis, or a weakened immune system.

Who Should Avoid TALTZ?

TALTZ may not be suitable if you are allergic to ixekizumab or any of its ingredients, have an active infection such as TB, or are pregnant or breastfeeding (discuss with your doctor).

Important Precautions

Vaccines: Avoid live vaccines while using TALTZ.
Surgery or Illness: Inform your doctor if you are scheduled for surgery or feel unwell.

How to Store TALTZ

Keep TALTZ in the refrigerator (36°F to 46°F). If needed, you can store it at room temperature (up to 86°F) for a maximum of 5 days. Do not freeze or expose to direct sunlight. Keep out of reach of children.

Frequently Asked Questions (FAQs)

Can I use TALTZ during pregnancy?
The effects of TALTZ during pregnancy are not well-known. Let your doctor know if you are pregnant or planning to become pregnant.

How long will it take to see results?
Most people notice improvements within 12 weeks. For some, it may be quicker or take a bit longer.

What if I have an infection?
TALTZ may increase your risk of infections. Let your doctor know if you have a fever, cough, or other symptoms of an infection before taking your next dose.

Need Help or More Information?
Speak to your doctor or pharmacist.

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Reference: Taltz Canada product monograph

To use the TALTZ autoinjector, remove it from the refrigerator 30 minutes before injection. Choose a clean injection site (thigh, abdomen, or outer upper arm). Inspect the liquid to ensure it is clear or slightly yellow. Place the autoinjector at a 90-degree angle to your skin, press firmly, and activate. Wait for the click indicating completion. Dispose of the used autoinjector in a puncture-resistant container. Follow your doctor’s instructions.