Category	Detailed Information
Medication Name	Vyzulta
Generic Name	Latanoprostene Bunod
Medication Class	Prostaglandin analog
Purpose	Vyzulta is used to lower intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension, helping to prevent vision loss or blindness.
Indications	– Open-angle glaucoma – Ocular hypertension
Mechanism of Action	Vyzulta increases the drainage of aqueous humor (the fluid inside the eye), which lowers the pressure within the eye by acting on two different pathways. This helps protect the optic nerve from damage.
Dosage Form	Eye drops
Solution Strength	0.024% (240 micrograms per mL)
Administration Frequency	Once daily, preferably in the evening
How to Use Vyzulta	1. Wash Your Hands: Always wash your hands before applying the drops. 2. Tilt Your Head Back: Look up and gently pull down the lower eyelid to create a small pocket. 3. Apply the Drop: Hold the dropper above the eye and squeeze one drop into the pocket. Avoid touching the dropper tip to your eye or any surface. 4. Close Your Eye: Gently close your eye and press the inside corner (near the nose) for 1-2 minutes. This helps keep the medicine from draining out of the eye. 5. Wipe Off Excess: Wipe away any excess liquid with a clean tissue.
What to Do if You Miss a Dose	If you forget to use Vyzulta, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not use extra drops to make up for the missed dose.
Possible Side Effects	– Common: Eye redness, increased brown pigmentation of the iris (may cause permanent eye color change), mild eye discomfort, blurred vision, increased eyelash growth. – Less Common: Eye pain, sensitivity to light, changes in eyelid skin color. – Rare: Severe eye irritation, vision changes, allergic reactions (such as swelling, itching, or difficulty breathing).
Storage Instructions	Store Vyzulta at room temperature (68°F to 77°F or 20°C to 25°C). Keep the bottle tightly closed when not in use. Protect from light and moisture. Do not use after the expiration date on the bottle.
Precautions and Warnings	– Contact Lenses: Remove contact lenses before applying Vyzulta. Wait at least 15 minutes before reinserting them. – Eye Color Changes: Vyzulta may cause gradual changes in eye color by increasing the amount of brown pigment in the iris, which could be permanent. – Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using Vyzulta. – Allergic Reactions: Stop using Vyzulta and seek medical attention if you experience signs of an allergic reaction, such as swelling, rash, or difficulty breathing.
When to Contact Your Doctor	– If you experience severe eye irritation, pain, or swelling. – If you notice significant changes in your vision, including blurred or tunnel vision. – If you develop any signs of an allergic reaction. – If you experience eye trauma or infection, as you may need to stop using the drops temporarily.
Other Considerations	– Interactions: Inform your doctor of all medications and supplements you are taking, as Vyzulta may interact with other eye medications or systemic drugs. – Driving and Using Machines: Vyzulta may cause temporary blurred vision after use. Do not drive or operate heavy machinery until your vision is clear.
Follow-Up	Regular follow-up appointments with your eye doctor are important to monitor your intraocular pressure and assess the effectiveness of Vyzulta.

Vyzulta (Latanoprostene bunod)

Vyzulta (Latanoprostene bunod)

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