Zoryve Cream (Roflumilast)

Buy Zoryve Cream from Canada

Zoryve Cream (Roflumilast)

Roflumilast

Product information

ZORYVE (roflumilast 0.3%) is a prescription cream used once daily to treat plaque psoriasis in individuals aged 12 and older, including sensitive skin areas. It works by reducing inflammation through PDE-4 enzyme inhibition. Common side effects include headache, diarrhea, and site irritation. ZORYVE is for external use only and should be stored at 59°F to 86°F. Do not use if you have severe liver issues or are allergic to its ingredients.

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You may order up to 90 days of medication at a time. All prices are in USD.

Zoryve Cream (Roflumilast) – Product Information


What is ZORYVE?

ZORYVE is a prescription cream used to treat plaque psoriasis in adults and children aged 12 years and older. It is safe to use on most parts of the body, including sensitive areas like the underarms, under the breasts, groin, and buttocks.


How Does It Work?

ZORYVE helps calm inflammation by blocking an enzyme (PDE-4) involved in psoriasis. This helps reduce redness, scaling, and itchiness in the skin.


How to Use ZORYVE

  • Apply once daily to affected areas.

  • Gently rub in completely until no cream is visible.

  • Wash your hands after applying—unless you're treating your hands.

  • If someone else applies the cream, they should also wash their hands after.

  • For external use only. Do not apply to the eyes, mouth, inside the vagina, or on broken skin.

  • If you forget to apply it, skip the missed dose and continue as usual the next day.


Do Not Use ZORYVE If:

  • You have moderate or severe liver problems.

  • You are allergic to roflumilast or any of the cream’s ingredients.


Before Using ZORYVE, Tell Your Doctor If You:

  • Are pregnant or trying to become pregnant.

  • Are breastfeeding or plan to breastfeed.
    → If using while breastfeeding, apply only to the smallest area for the shortest time needed.
    → Do not apply to the nipple or areola to avoid exposing your baby to the medicine.


Possible Side Effects


Common side effects may include:

  • Diarrhea

  • Headache

  • Trouble sleeping

  • Nausea

  • Pain or stinging where the cream is applied

  • Mild weight loss

Rare but more serious side effects (mostly seen with the pill version of this medication):

  • Dizziness or tremor

  • Fast or irregular heartbeat

  • Mood changes like anxiety or depression

If any side effect bothers you or doesn’t go away, talk to your healthcare provider.


Tell Your Doctor If You Take:

  • Erythromycin (for infections)

  • Ketoconazole (for fungal infections)

  • Fluvoxamine (for depression)

  • Cimetidine (for heartburn)

  • Enoxacin (for bacterial infections)

  • Birth control pills with gestodene and ethinyl estradiol

These may increase the amount of medication in your body and raise the risk of side effects.


Storage

  • Store at 59°F to 86°F.
  • Keep the tube tightly closed and out of reach of children.

Reference: Zoryve Cream Canada product Monograph