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Why Pay More for Jardiance? Save Big with DrugsByCanada.com!
If you’re tired of overpaying for your Jardiance (empagliflozin) prescription, it’s time to switch to DrugsByCanada.com. We provide the same FDA-approved Jardiance you trust, shipped directly from Winnipeg, Manitoba in Canada, at a fraction of the cost. Thanks to Canada’s stringent regulations, you receive top-quality medication without the hefty price tag.
Understanding Jardiance: Support for Those Managing Type 2 Diabetes
Managing Type 2 diabetes can be challenging, affecting your daily life and overall health. Jardiance is designed to help control blood sugar levels and reduce the risk of cardiovascular events in adults with Type 2 diabetes. By improving glycemic control, Jardiance can help you manage your condition more effectively and lead a healthier life.
We understand how tough it can be to manage diabetes, and we believe that effective treatment shouldn’t come with an overwhelming financial burden. That’s why we’re committed to offering Jardiance at prices that are accessible, so you can focus on what truly matters—your health and well-being.
Many Americans are amazed at how much they can save by ordering their Jardiance through us. Why pay more for the same medication? Whether you’re dealing with expensive local pharmacies or so-called “discount” drug cards, our prices are unmatched. We offer unbeatable savings without compromising on quality.
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Bonus Alert: We’ve got something special for you! Use Coupon Code: JARSAVE at checkout to save! We’ll waive the $15 shipping charge on your Jardiance orders. It’s our way of saying thank you for choosing DrugsByCanada.com as your go-to source for affordable, high-quality Jardiance.
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If you have any questions about this offer, please phone us toll free at 1-888-349-5925 or email support@drugsbycanada.com
Pharmaceutical Facts on Jardiance Tablets
Category | Details |
---|---|
Generic Name | Empagliflozin |
Brand Name | Jardiance |
Drug Class | Sodium-glucose co-transporter 2 (SGLT2) inhibitor |
Indication | – Treatment of type 2 diabetes mellitus to improve glycemic control in adults |
– Reduction of cardiovascular death in adults with type 2 diabetes mellitus and established cardiovascular disease | |
Other Indications | – To reduce the risk of hospitalization for heart failure in adults with type 2 diabetes and cardiovascular disease |
Formulation | Oral tablet |
Common Dosages | 10 mg, 25 mg |
Mechanism of Action | Inhibits SGLT2 in the proximal renal tubules, reducing reabsorption of filtered glucose and lowering blood glucose levels |
Pharmacokinetics | – Absorption: Rapid absorption with peak plasma concentration in 1.5 hours |
– Half-life: Approximately 12 hours | |
– Metabolism: Primarily via glucuronidation by UGT2B7, UGT1A3; minor CYP3A4 metabolism | |
– Excretion: Primarily renal (urine) and to a lesser extent via feces | |
Administration | – Taken orally once daily in the morning, with or without food |
– Missed dose: Take as soon as remembered on the same day; do not double dose | |
Common Side Effects | – Urinary tract infections |
– Increased urination | |
– Genital fungal infections | |
– Dyslipidemia | |
– Thirst | |
– Nausea | |
Serious Side Effects | – Ketoacidosis (rare but serious) |
– Hypotension | |
– Acute kidney injury | |
– Urosepsis and pyelonephritis | |
– Fournier’s gangrene (necrotizing fasciitis of the perineum) | |
– Hypersensitivity reactions (angioedema, rash) | |
Contraindications | – Severe renal impairment (eGFR <30 mL/min/1.73 m²), end-stage renal disease, or dialysis |
– Hypersensitivity to empagliflozin or any component of Jardiance | |
– Patients with a history of serious hypersensitivity reactions to the drug | |
Special Populations | – Elderly: Increased risk of volume depletion and renal impairment; monitor closely |
– Renal Impairment: Contraindicated in severe impairment; dosage adjustment not required in mild to moderate impairment | |
– Hepatic Impairment: No dose adjustment required | |
– Pediatrics: Safety and efficacy not established in patients under 18 years of age | |
Monitoring | – Monitor renal function (eGFR) prior to initiation and periodically during treatment |
– Monitor for signs and symptoms of ketoacidosis, especially during periods of stress or illness | |
– Monitor blood pressure, especially in patients with volume depletion | |
– Periodic assessment of lipid levels | |
Pregnancy Category | Not assigned (use only if the potential benefit justifies the potential risk to the fetus) |
Lactation | It is unknown if Jardiance is excreted in human milk; consider the benefits and risks of use during breastfeeding |
Drug Interactions | – Diuretics: Increased risk of dehydration and hypotension |
– Insulin and Insulin Secretagogues: Increased risk of hypoglycemia | |
– Rifampin: May decrease Jardiance exposure and effectiveness | |
– Digoxin: Jardiance may increase digoxin levels; monitor closely | |
Overdose Management | – Symptomatic and supportive treatment |
– Monitor renal function and electrolytes | |
– Consider dialysis in cases of severe overdose as the drug is moderately dialyzable | |
Special Precautions | – Volume Depletion: Correct hypovolemia prior to initiation; monitor for signs of hypotension |
– Ketoacidosis: Assess patients for ketoacidosis during periods of acute illness, stress, or reduced food intake | |
– Renal Impairment: Increased risk of acute kidney injury; monitor renal function closely | |
– Fournier’s Gangrene: Rare but serious; seek immediate medical attention if symptoms occur | |
Storage | – Store at room temperature (20-25°C or 68-77°F) |
– Protect from moisture | |
– Keep out of reach of children | |
Manufacturer | Boehringer Ingelheim and Eli Lilly |
Approval Year | 2014 |
Market Availability | Widely available in the US and internationally |
Patent Expiry | Expected patent expiry in the US is 2029 |