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Cuprimine (Penicillamine) for Veterinary Use: Fact Table
Category | Details |
---|---|
Generic Name | Penicillamine |
Brand Name | Cuprimine |
Veterinary Use | Used primarily for treating copper storage diseases and sometimes for immune-mediated conditions in dogs and cats |
Form | Oral capsules or tablets |
Strengths Available | Typically 250 mg capsules/tablets |
Mechanism of Action | Binds to copper and promotes its excretion in urine, also has immune-modulating properties |
Indications | – Copper storage disease (e.g., in Bedlington Terriers) |
– Wilson’s disease in animals (rare) | |
– Rheumatoid-like arthritis in dogs (off-label) | |
– Systemic lupus erythematosus in dogs (off-label) | |
Dosage | Varies by condition and species; typically prescribed by a veterinarian based on weight and severity of condition |
Administration | Oral; given with or without food as directed by a veterinarian |
Side Effects | – Loss of appetite |
– Vomiting | |
– Diarrhea | |
– Skin rashes or itching | |
– Proteinuria (excess protein in urine) | |
– Potential for bone marrow suppression (rare) | |
Contraindications | – Known hypersensitivity to penicillamine |
– Severe renal impairment | |
Monitoring | Regular blood tests (complete blood count, liver and kidney function tests) and urine tests are recommended during treatment |
Drug Interactions | – Antacids (may reduce absorption) |
– Iron supplements (may reduce effectiveness) | |
Special Precautions | – Should be used with caution in animals with a history of bone marrow suppression or kidney disease |
Withdrawal Period | Not applicable as Cuprimine is not typically used in food-producing animals |
Storage | Store at room temperature, away from moisture and light |
Legal Status | Prescription only (Rx) |
Manufacturer | Produced by various manufacturers |
This fact table provides a comprehensive overview of Cuprimine (penicillamine) for veterinary use, focusing on its application for treating conditions like copper storage disease and other off-label uses in dogs and cats. Always consult a veterinarian for specific treatment and dosage guidelines tailored to your pet’s needs.